RajathaBhasma is an Ayurvedic supplement prepared from Silver useful in cardio-vascular diseases, improves skin complexion, digestion power, body strength and immunity. The present study deals with the synthesis, characterization and study of application of RajataBhasma. The synthesized bhasma was subjected to physical and structural characterization studies. Application of nanosilver has been studies with RajathaBhasma in order to evaluate use a medicinal supplement. The characterization of prepared bhasma was also done by using modern analytical techniques such as EDAX, SEM, XRD, FTIR, which shows that Rajathabhasma mainly consists of silver in nano size. Application studies like antimicrobial, antioxidant studies reveal that high potency of RajathaBhasma use as medicinal supplement.